Usual Adult Tramadol Dose for Pain:
For mild to moderate severe chronic pain not requiring rapid onset of analgesic effect:
Initial dose: 25 mg every morning
Titration: increase in 25 mg increments as separate doses every 3 days
to reach 100 mg per day taken as 25 mg 4 times per day. Then the total
daily dose may be increased by 50 mg as tolerated every 3 days to reach
200 mg per day taken as 50 mg 4 times per day.
Maintenance: After titration, tramadol 50 mg to 100 mg can be
administered as needed for pain relief every 4 to 6 hours not to exceed
400 mg per day.
For the management of moderate to moderately severe chronic pain in
adults who require around-the-clock treatment of their pain for an
extended period of time:
Extended-Release Tablets:
Initial Dose: 100 mg once daily and titrated up as necessary by 100 mg
increments every five days to relief of pain and depending upon
tolerability.
Maximum Dose: Extended-release tablets should not be administered at a dose exceeding 300 mg per day.
For patients in whom rapid onset of analgesic effect is required and for
whom the benefits outweigh the risk of discontinuation due to adverse
events associated with higher initial dose:
Dose: 50 mg to 100 mg can be administered as needed for pain relief every 4 to 6 hours, not to exceed 400 mg per day.
Usual Geriatric Tramadol Dose for Pain:
For patients over 65 years:
Dose selection should be cautious, usually starting at the low end of
the dosing range, reflecting the greater frequency of decreased hepatic,
renal, or cardiac function and of concomitant disease or other drug
therapy.
For patients over 75 years:
Maximum dose of regular oral tablets: 300 mg per day in divided doses
Usual Pediatric Tramadol Dose for Pain:
16 years old and up:
Brand name: Ryzolt
Initial: 100 mg once daily
Titrate by 100 mg increments every 2 to 3 days if needed for pain control
Maximum: 300 mg/day
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