You may be more likely to have a seizure (convulsions) if you take
tramadol while you are using certain other medicines. Do not take
tramadol without telling your doctor if you also use any of the
following medications:
-
an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine
(Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam); or
-
an antidepressant such as amitriptyline (Elavil, Vanatrip),
citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin),
escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine
(Luvox), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine
(Paxil), or sertraline (Zoloft).
Cold or allergy medicine, sleeping pills, muscle relaxers, and medicine
for seizures or anxiety can add to sleepiness caused by tramadol. Tell
your doctor if you regularly use any of these medicines, or any other
pain medication.
Tell your doctor about all other medicines you use, especially:
-
carbamazepine (Carbatrol, Equetro, Tegretol);
-
lithium (Eskalith, LithoBid);
-
ADHD medications (Adderall, Ritalin, Strattera);
-
an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S.,
EryPed, Ery-Tab, Erythrocin, Pediazole), linezolid (Zyvox), rifampin
(Rifadin, Rimactane, Rifater); or telithromycin (Ketek);
-
antifungal medication such as clotrimazole (Mycelex Troche),
itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig), or
voriconazole (Vfend);
-
cancer medications such as gefitinib (Iressa), imatinib (Gleevec), or nilotinib (Tasigna);
-
a heart rhythm medication such as amiodarone (Cordarone, Pacerone),
flecainide (Tambocor), propafenone (Rythmol), or quinidine (Quin-G);
-
heart or blood pressure medication such as diltiazem (Cartia,
Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia),
verapamil (Calan, Covera, Isoptin, Verelan), and others;
-
HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine
(Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir
(Viracept), saquinavir (Invirase), or ritonavir (Norvir, Kaletra); or
-
migraine headache medicine such as sumatriptan (Imitrex, Treximet).
This list is not complete and there are many other drugs that can
interact with tramadol. Tell your doctor about all medications you use.
This includes prescription, over-the-counter, vitamin, and herbal
products. Do not start a new medication without telling your doctor.
Keep a list of all your medicines and show it to any healthcare provider
who treats you.
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